I'm writing a story about someone who's poisoned with a drug which makes him not be able to sleep for several days. In order to make my story as realistic as possible I need to know a couple of things:

1) Does this type of drug actually exist? I think that amphetamines or modafinil can keep you awake but,

2) Can these drugs keep the effect for a long time (days)? I mean, the organism would start at a certain point and try to sleep, right?

3) If there's such a drug then after a long period of sleep deprivation the person would start to have certain symptoms. Could be hallucinations one of these symptoms?

4) And now even more complicated: is there any possibility that if the person dies could be no trace of the drug in an autopsy's toxicological analysis?

1 Answer 1


The most popular drug that can keep people awake for long time is caffeine. Most caffeine pills contain a 200mg dose, about the same as the average 12-ounce cup of coffee.

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