I have strep group A. My doctor gave me Penicillin V Potassium 500 MG to take once every 12 hours. It's 3 pm in my time zone, which means the next dose would be 3 AM. Does it make sense to take the next dose at like 11 PM or Midnight, and then again in the late morning, or should I take the next dose first thing in the morning (like 8 AM)? Or should I set an alarm and take it in the middle of the night (I'd rather NOT do that for the full course!)
Is there a general way to know whether to err on the side of slightly more or less often, or whether it should be very exact?