Does the "black" ink of a ballpoint pen affect my health in any way, especially if it's applied in the same general area over a larger period of time?
- It is usually only a problem in Ink poisoning:
Writing ink poisoning occurs when someone swallows ink found in writing instruments (pens).
Allergies to skin: Irritation to skin, burning or itching. Which are rare the main adverse effect is usually only staining do the dye in the ink.
The primary concern with writing on skin with permanent ink is that permanent ink may contain xylene. Xylene is a toxic substance, though toxicity is normally linked to inhalation.
People can cause damage to their skin however, by cutting the skin and then writing on skin with a permanent marker.
- I can find no evidence of a greater problem over time, unless you were referring to developing a allergy which is possible, but I found no evidence to support that statement.
FDA.gov - About Tattoo ink