Timeline for Does antigen expression from an mRNA vaccine damage the host cell?
Current License: CC BY-SA 4.0
7 events
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| Mar 25, 2022 at 13:19 | comment | added | Peter Bernhard | Also, I want to draw the attention to some basic understanding: what is need for immunity to arise is "priming". That word is rarely heard, in contrast to "presentation" - you say "surface feature" which is pleasing. | |
| Mar 25, 2022 at 13:15 | comment | added | Peter Bernhard | One way to ask may be: Is presentation to immune cell on surface (on MHC that is) the effect or the cause of immanent cell death? Alternatively, if you delete all killer cells will a cell that presents antigen on its surface (in MHC context) survive? My idea I consider some paradox: The more symbiotic the viral infection and the interaction with the host is the more it is necessary to have killer cells attracted to that site to stop this (The less viral infection as such leads to cell death the more the killing is needed, the more the presentation on MHC seems against single cell's will.) | |
| Mar 25, 2022 at 13:10 | comment | added | Peter Bernhard | It's barely known that viral antigen/m-RNA-antigen can be become a "surface feature" in a narrow sense as it may be expressed outside the so called - immunizing - MHC. I cannot tell if CoV-19 is some special case, I found it surprising that infected cells use viral antigen as somehow "handy" "surface feature" for cell to cell signaling (search word is syncytium, syncytia, I recommend). | |
| Sep 27, 2021 at 20:12 | history | edited | endolith | CC BY-SA 4.0 |
added 25 characters in body
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| May 20, 2021 at 23:07 | comment | added | Anthony X | So a key point here is that the manufactured proteins are not attacked by the immune system as discrete particles but as surface features of a cell. | |
| May 20, 2021 at 3:28 | review | First posts | |||
| Jun 3, 2021 at 3:26 | |||||
| May 20, 2021 at 3:26 | history | answered | endolith | CC BY-SA 4.0 |