Timeline for Covid-19 spike protein as vaccine?
Current License: CC BY-SA 4.0
8 events
| when toggle format | what | by | license | comment | |
|---|---|---|---|---|---|
| Mar 21, 2020 at 19:13 | comment | added | Graham Chiu | Ok. medrxiv.org/content/10.1101/2020.02.29.20029520v1 | |
| Mar 21, 2020 at 18:52 | comment | added | Charles | @GrahamChiu Direct cause of death is usually ARDS; cytokine storm/sHLH is probably #2. But my claim wasn't about proximal cause of death but involvement. There are plenty of references out there; take for example "COVID-19: consider cytokine storm syndromes and immunosuppression" (The Lancet) or "Immune responses in COVID-19 and potential vaccines: Lessons learned from SARS and MERS epidemic" (Asian Pacific Journal of Allergy and Immunology). | |
| Mar 21, 2020 at 15:57 | comment | added | Graham Chiu | What's the reference that main cause of death is by cytokine storm vs viral pneumonia? | |
| Mar 20, 2020 at 0:18 | comment | added | Charles | @DonSlowik There's lots of in vitro work that can be done, but until you test in vivo you don't really know, because there are a lot of pieces and they work together in a complicated way. | |
| Mar 19, 2020 at 21:14 | comment | added | Don Slowik | Is there a way of determining the immune system response other than looking for one in a living animal? | |
| Mar 19, 2020 at 20:43 | comment | added | Mark | To apply this to this specific case, it could be that the spike proteins themselves trigger a cytokine storm in a fraction of the population, or there could be something about the protein configuration that makes it entirely invisible to the immune system. In either case, we'd need to pick something else as a vaccine target. | |
| Mar 19, 2020 at 20:15 | review | First posts | |||
| Apr 1, 2020 at 2:47 | |||||
| Mar 19, 2020 at 20:13 | history | answered | Charles | CC BY-SA 4.0 |